| Double Down Video Poker ©1991 Sam Hazan Strategy Cards
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| Double Link v1.02 ©1991 Paul R. Tupaczewski Action Strategy
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| Double Link ©1991 Paul R. Tupaczewski Action Strategy
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| Double Mind ©1991 Art&Fun GMBH Strategy
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| Dr. Rudy ©1991 Kevin J. North Action Strategy
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| Drachen von Laas ©1991 Attic Entertainment Software GmbH Adventure Interactive Fiction
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| Dragon ©1991 H. Wilhelm Strategy
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| Dragon Spirit- The New Legend ©1991 Domark Software Ltd. Action
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| Dragon's Lair II- Escape from Singe's Castle ©1991 ReadySoft Incorporated Action
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| Dragonflight ©1991 Thalion Software RPG
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| Dragonriders of Pern ©1991 Everlasting Software Strategy
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| DrawSome ©1991 AssistWare Educational
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| Dream Team, The- 3 on 3 Challenge ©1991 Data East USA, Inc. Sports
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| DressMeUp ©1991 Christopher G. Gunn Educational
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| Dropper ©1991 LocIS Strategy Action
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| Duel 2000 ©1991 Damon Hastings Action
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| Duel to the Death ©1991 David Sherohman Strategy
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| Duke Nukem- Episode One- Shrapnel City ©1991 Apogee Software, Ltd. Action
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| Duke Nukem- Episode Three- Trapped in the Future! ©1991 Apogee Software, Ltd. Action
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| Duke Nukem- Episode Two- Mission- Moonbase ©1991 Apogee Software, Ltd. Action
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| Duke Nukum- Episode One- Shrapnel City ©1991 Apogee Software, Ltd. Action
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| Duke Nukum- Episode Three- Trapped in the Future! ©1991 Apogee Software, Ltd. Action
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| Duke Nukum- Episode Two- Mission- Moonbase ©1991 Apogee Software, Ltd. Action
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| Dungeon Thief vD.5 ©1991 Sente Systems, Inc. Adventure Action
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| Dungeons of Drakklor ©1991 Mark Neri Action
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| Duromer ©1991 Timur Gulayev Educational
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| Dusk of the Gods ©1991 Interstel Corporation Educational RPG Adventure
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| Dvorak on Typing ©1991 Interplay Productions, Inc. Educational
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| E.S.S Mega ©1991 Tomahawk Simulation
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| Eagle's Rider ©1991 Microids Action Adventure
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| Earl Weaver Baseball II ©1991 Electronic Arts Ltd. Sports
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| ECO - Ejercicios con ordenador ©1991 J.A. Munoz Lopez Educational
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| Eco Phantoms ©1991 Electronic Zoo Action Adventure Strategy
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| Eco-Saurus ©1991 First Byte Educational
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| EGA Mouse Paint ©1991 Flying Mouse Software Educational
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| EGA Shogi ©1991 Ray Gillman Strategy
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| EGA-Pyramid ©1991 John A. Junod Strategy Cards
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| Egawheel ©1991 Russel Mueller Strategy
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| Electric Crayon 3.0- Inspector Gadget- Safety Patrol ©1991 Merit Software Educational Editor
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| Electric Crayon 3.0- Super Mario Bros & Friends- When I Grow Up ©1991 Merit Software Educational Editor
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| Electric Jigsaw ©1991 Merit Software Inc. Strategy Puzzle
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| Electronic Aggravation ©1991 SimoneSystems Software Strategy
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| Elf ©1991 Ocean Software Ltd. Action
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| Eliminator ©1991 Jerry Judd Action
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| Elite Plus ©1991 Microplay Software Simulation
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